Understanding Financial Barriers to Getting More Coverage for Patients in Clinical Trials

Trevan Locke is an Assistant Research Director at Duke-Margolis working on issues related to biomedical innovation and clinical research. He oversees Duke-Margolis' involvement as a founding member of the Advancing Clinical Trials at the Point of Care Coalition and workstreams on evidence generation for Duke-Margolis' Real-World Evidence Collaborative. Previously, he worked as a Regulatory Science and Policy Analyst at the American Association for Cancer Research on regulatory issues impacting the development of cancer therapies, including considerations for equitable clinical trial enrollment. Dr. Locke completed a Bachelor of Engineering in Chemical and Biomolecular Engineering at Vanderbilt University and a PhD in Chemical and Biochemical Engineering at Rutgers University.

Donna M. O’Brien, MHA, is a National Advisor with Manatt Health providing strategy development and program implementation advice to healthcare providers and research institutes. Prior to this, Donna served as Consultant to the Director of the NCI for nine years to support the development and implementation of a new program model for cancer care delivery and research expansion in 30 hospitals in 22 states. She was a member of the team that designed the NCI Community Oncology Research Program (NCORP). She was also an executive at MD Anderson Cancer Center in Houston and Executive Vice President of the Catholic Health Long Island.

After spending time in public health and clinical nutrition, Denise started work at Duke as a clinical research coordinator in 2000 for NIH funded trials in oncology. In 2009, her Research Management Team in the School of Nursing received support from Duke’s CTSA to leverage the group’s services and launch REDCap for the School of Medicine. For 10 years, Ms Synder has been the Associate Dean for Clinical Research for Duke University School of Medicine. In this role, she leads the Duke Office of Clinical Research (DOCR), a central support office of expertise in coverage analysis, study logistics, data management, regulatory oversight, workforce innovation, and guidance for clinical research operations for Duke as a site.