Rational Combinations 360° Speakers
Joyson Karakunnel, MD, MSc, FACP
Medical Director & Advisor / VP & Head of Clinical Development
Parker Institute / Arcus Biosciences
Joyson Karakunnel, MD, MSc, FACP, is an experienced medical oncologist and hematologist with drug development expertise both in academics and industry. Prior to joining industry, he was an investigator in clinical trials at the NCI and team leader for the hematologic group at Walter Reed National Military Medical Center. He later joined AZ/Medimmune to lead some of the key phase 1/1b clinical trials with immunomodulators including PDL1 and CTLA4 agonists both as single agents and in combinations in solid tumors which supported the development of phase 3 randomized trials in multiple indications. Dr Karakunnel was also leading the development of those agents in hematological malignancies in addition to conducting studies at Medimmune with external partners such as Celgene and Innate. He was an Associate Professor at the Uniformed Services University of the Health Sciences and medical reviewer at the FDA. Dr Karakunnel continues to treat patients in clinical practice. He completed his medical training at Annamalai University in Tamil Nadu, India, internal medicine residency at Overlook Hospital/UMDNJ where he was chief resident and completed fellowships in Hematology, Oncology and Pain and Palliative Care at the National Cancer Institute. He holds a Masters in pharmacology from the University of Maryland and is a member of Phi Beta Kappa. He was elected to be a Fellow in the American College of Physicians. Dr Karakunnel has been a co-author on several papers, book chapters and given several invited oral presentations at conferences and academic centers.